Many of my fears around help-seeking from health professionals are linked to a lack of trust that they are well-informed about the interventions they offer. Links here will gather together latest evidence on available treatment options.

Pharmacological interventions
Newer antidepressants for depression in children and adolescents, 14 November 2012, Cochrane Summaries. “Overall, there was evidence that those treated with an antidepressant had lower depression severity scores and higher rates of response/remission than those on placebo. However, the size of these effects was small … [and] there was evidence of an increased risk (58%) of suicide-related outcome.”
Sertraline versus other antidepressive agents for depression, 14 April 2010, Cochrane Summaries. “Evidence favouring sertraline over some other antidepressants for the acute phase treatment of major depression was found, either in terms of efficacy (fluoxetine) or acceptability/tolerability (amitriptyline, imipramine, paroxetine and mirtazapine). However, some differences favouring newer antidepressants in terms of efficacy (mirtazapine) and acceptability (bupropion) were also found. In terms of individual side effects, sertraline was generally associated with a higher rate of participants experiencing diarrhoea.”
Escitalopram versus other antidepressive agents for depression, 7 October 2009, Cochrane Summaries. “Escitalopram appears to be suitable as first-line antidepressant treatment for people with moderate to severe major depression… it did perform better than citalopram when we brought together the results of six studies in nearly two thousand patients.”

Psychological interventions

Other interventions
Should you get a genetic test to see if you’re at risk for developing a mental illness?, September 2012, Black Dog Institute, Australia. Article based on evidence from: Wilde A, Mitchell PB, Meiser B, Schofield PR, Implications of the Use of Genetic Tests in Psychiatry, with a Focus on Major Depressive Disorder: A review, 2012Depression & Anxiety, 14 September 2012.

> Orchids, dandelions and an intriguing set of genes, 22 April 2012, All In The Mind, ABC Radio National Australia

I’m an activist at heart, and being involved in campaigning and advocacy has often been helpful for me.

Mind have done some much needed research, highlighting a postcode lottery of crisis care in the UK.  Find out what crisis care is like in your area and lobby your MP for change.


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